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Depression and anxiety are the world’s leading disabilities; recent studies show that one in six people are prescribed psychiatric drugs, and SSRI’s are the second-most common medication taken worldwide. Naturopathic physicians are in the perfect position to offer alternative support to this population of patients, mainly because they spend more than 8-10 minutes per visit with their patients, and thus can help identify underlying causes, and avoid Band-Aid solutions. What follows are some tips and recommendations to help you optimise your patients’ mental health.
Sanesco Neurotransmitter Testing: Sanesco and Neurolab have provided a large cohort (over 20,000 patients) study of data collected over the past 10 years, to validate the clinical application of urinary neurotransmitter testing, as well as non-drug interventions, to effectively support patients. (Sample report from Sanesco). You may want to consider this testing for your difficult patients who seriously want to get off their medications. Two retests are recommended within 8 months to help you navigate through the three phases of treatment, and achieve optimal HPA axis function.
Sanesco Tranquilent ($24.15 for 30 tabs): this chewable inositol 1000 mg, L-theanine 25 mg and 5-HTP 20 mg combination is effective for pediatrics (not more than 2 per day: see dosing recommendations) and adults (up to 8 per day). It is effective in the treatment of anxiety and obsessive thoughts, and supports serotonin and GABA production in the body. I encourage patients to keep these in their purse or desk and take as needed throughout the day and especially in the evening to help with sleep.
Sanesco Prolent ($56.95 for 60 caps): studies have shown that it is effective in crossing blood-brain barrier to promote melatonin and serotonin production, and help with blood sugar regulation. It contains NSB, a proprietary blend of plant-based fermenting enzymes, and has been shown to reduce toxins and enzyme inhibitors, making them more effective. Bioperine® in NSB™ formulas is another way Sanesco® aims to ensure optimal absorption and efficacy of its nutraceuticals. Not only has piperine been shown to improve digestion, but it also enhances neurological function. Piperine has shown anti-depressant-like activity by increasing the synthesis of 5-HT (serotonin) from 5-HTP (an ingredient in Prolent™)[xviii]. Studies have found that MPTP (associated with Parkinson’s disease) is inhibited by piperine, making it neuroprotective against Parkinson’s disease [xix]. Piperine is also thought to be neuroprotective to the hippocampus, a part of the brain essential for cognition and memory.
Prolent contains B6 20 mg, L-theanine 75 mg and 5-HTP 50 mg. Patients need to be monitored carefully when combining with SSRI’s. Dosed at two caps, taken in the evening or before lunch or dinner for cravings.
Other areas to support when treating anxiety and depression:
- Basic support for any anxiety and depression case: the treatment plan should include a B complex; Nordic Naturals Ultimate Omega fish oils or Vital Nutrients Ultra Pure Fish oil: 3000 mg per day; magnesium (Jigsaw Mag SRT), especially taken at bedtime for restless and poor quality sleep; and a multi vitamin and mineral complex (Vital Nutrients: Minimal and Essential). It has amazed me over the years how the above can help in a matter of weeks! Most people who live off the SAD (Standard American Diet) are terribly deficient. Many females are low in iron with serum ferritin less than 60. Once this is treated they feel so much better. (Vital Nutrients: Iron plus C)
- Adrenal fatigue: measure level of adrenal fatigue and burnout using salivary testing. Cortisol and DHEA levels can be measured as in the Sanesco testing. MediHerb Combinations to consider: AdrenoCo and Withania Complex (if no blood pressure issues) and Rhodiola & Ginseng.
- Thyroid support: many female patients do not have ideal levels of TSH, T3 and T4. Check for autoimmune disease with TPO. See recent blog on thyroid support.
- Brain support: for brain fatigue consider: Bacopa Complex and Ginkgo. Kerry Bone has told us he takes up to 9 per day of ginkgo when he is travelling and lecturing. Anyone over the age of 50 might want to take ginkgo to prevent strokes and MCD (mild cognitive decline). Lions Mane, according to recent research, increases BDNF (brain-derived neuro-factors) in the brain and enhances memory.
- Anxiety and Insomnia: Kava Forte, Valerian Complex, St. John’s Wort (be careful of light sensitivity in summer months and is great for SAD: Seasonal Affective Disorder), Nevaton Forte or Mag SRT. The goal is 8 hours of restful sleep per night.
- Hormone support: women in peri-menopause and menopause need added support in addition to the above. Consider FemCo, Chaste Tree, Tribulus Forte, Wild Yam Complex and Withania Complex. Consider Vital Nutrients: Menopause Support or Mediherb Wild Yam Complex for hot flushes.
- Blood sugar regulation: Gymnema helps with cravings and blood sugar regulation. Dream Protein mixed with Greens First can be used as a morning smoothie for those too stressed or rushed to eat breakfast. It will maintain blood sugar until lunchtime. Even some children will take this combination especially before playing sports. A diet high in protein helps with blood sugar regulation and sugar cravings.
- Depression; Mediherb St. John’s Wort provides high levels of “flavonoid glycosides” which increase the bioavailabilty of hypericin, the main active ingredient in St. John’s Wort, to help with depression. Liquid St. John’s Wort does NOT contain any hyperforin.
- Food sensitivities: some foods can cause fatigue, anxiety and depression. A gluten-free diet, according to Dr. Mark Hyman in his “Broken Brain” docuseries, is the best diet for depression and anxiety.
- Parasympathetic balancing: unplugging from devices, exercise, yoga, meditation, and the Arts are all great for lowering cortisol. When patients are prescribed “The Arts”, visits to MD’s and hospitals are reduced by up to 40%! (Read my 30 Day Intentions handout!).
Until next month!
Nascent iodine is a supplemental form of iodine. Iodine is an essential mineral that the body requires for normal function. For nearly a century, nascent iodine has been regarded as a more effective form of the mineral than many dietary iodine forms, such as potassium iodide. In fact, most forms of dietary iodine become mere iodide in the digestive tract. This is important to note because iodides are not as easily absorbed and utilized by the body, meaning that iodine-dependent organs and processes may not be adequately supported. This is what makes nascent iodine such a popular form of iodine for supplementation. A defining characteristic of nascent iodine is that it is an atomic form of iodine with an incomplete number of electrons. This gives it an electromagnetic charge. It is also why nascent iodine is sometimes referred to as atomic iodine, monatomic iodine, or atomidine. Some manufacturers mix nascent iodine with other supplements (such as herbs) in the bottle, which would bond when this free form of iodide is exposed to a positively charged ion, such as sodium or potassium, as it would be in a liquid supplement, it will bind with these to form sodium iodide or potassium iodide, basically nullifying its nascent state.
Dr. Jonathon Wright has written many articles about the importance of iodine, see his article attached. In his experience, up to 9 drops of SSKI providing 625mcg per drop, of iodine will not suppress the thyroid. He uses it for hypothyroid, fibrocystic breast disease, recurrent urinary tract infections, purifying contaminated water in third world countries, prevents sinus infection and ovarian cysts. He has observed many hormone tests to see that iodine lowers the carcinogenic metabolites of estrone and 16-alpha hydroxestrone to the neutral form estriol. He has used for contractures such as Dupuytren’s and Peryonie’s disease when used in the early stages. When applied topically combined with DMSO or flaxoil topically can heal peri-anal and recto-vaginal fistulas, acne herpes simplex, sebaceous cysts as well as hemorrhoids. 3-4 drops in water daily dissolves parotid duct stones within 4-8 months. Iodine for COPD loosens bronchial secretions preventing bronchial infections.
Dr. Gabriel Cousens on the uses of Iodine:
The thyroid is only one gland of many glands and tissues that needs iodine. Other glands/organs/systems with high iodine uptake are the breasts, ovaries, cervix, blood, lymph, bones, gastric mucosal, salivary, adrenal, prostate, colon, thymus, lungs, bladder, kidney, and skin. In perspective, the thyroid holds 50 milligrams of iodine, the breasts hold 200 milligrams, the skin holds 400 milligrams of iodine, and the whole body holds 2000 milligrams, and possibly much more. Iodine is found and used in every hormonal receptor in the body.
Dr. Richard Kunin M.D. an expert on iodine recommends taking iodine with omega 3 and 6 essential fast as well as sulfur containing amino acid such as methionine and cysteine, normally found in a serving of animal protein.
With the increasing threat of antibiotic resistance world-wide iodine may be a good substitute to educate your patients about. It is anti-fungal, anti-bacterial and anti-viral. If you are recommending daily doses of more than 1-2 drops then monitor thyroid function. Iodine stains so watch your clothing when you apply it. Some have an allergy to iodine. Using the Nascent Form of iodine hold an electromagnetic charge which provides an energy release for 2-3 hours after consumed on an empty stomach. It is recommended to be consumed in the morning and before 4pm otherwise it might be too energizing for sleep. Always keep an eye on thyroid blood tests when adding iodine to a patient’s long term health protocol. See attached articles (Uranium, Parkinsons & Iodine) from the Enviromedica website the source of Promedics Nascent Iodine.
1) Iodine prevents heart disease. (perhaps the mechanism is that iodine makes oils and fats more water soluble, lessening artery clogging seen on retinal photomicrographs when combined with niacin “lodo-niacin).
2) Iodine eliminates toxic halogens from the body (including radioactive I-131).
3) Iodine supports apoptosis.
4) Iodine activates hormone receptors and helps prevent certain forms of cancer.
5) Iodine protects ATP function and enhances ATP production.
6) Iodine prevents fibrocystic breast disease.
7) Iodine decreases insulin needs in diabetics.
8) Iodine helps support protein synthesis.
9) Iodine deficiency is a global health threat.
10) Iodine destroys pathogens, molds, fungi, parasites, and malaria.
11) Iodine is needed with the use of cordless phones, cell phones and now smart meters to prevent hypothyroidism.
12) Iodine supports pregnancy (as the fetus undergoes more apoptosis than any other developmental stage).
13) Iodine regulates estrogen production in the ovaries.
14) Iodine is anti-mucolytic (meaning it reduces mucus catarrh).
15) Iodine neutralizes hydroxyl ions and hydrates the cells.
MediHerb Thyroid Support
Rehmania Complex (use this adaptogenic formula in those patients who cannot tolerate the licorice that is found in the Withania Complex), Withania tincture or Withania Complex (in animal studies shows promising thyroid stimulating activity in addition to its adaptogen effects), bladderwack (which contains iodine) and Bacopa Complex (in animal studies has been shown to stimulate thyroid function are the four main herbs to consider for the treatment of low thyroid function. Think of Withania Complex for “tired yet wired” patients and for those who can tolerate licorice. For additional adrenal support consider Rhodiola &Ginseng (for those patients who need an increase in physical as well as mental performance and help with glucose control) and AdrenoCo (for more severe adrenal exhaustion higher dosages of rehmania and licorice).
Ed: I often prefer liquid tinctures so my Female Adrenal tonic contains: withania, rehmania, shativari, astragalus, reishi and siberian ginseng. Alternating these herbs in combination long term has been a favorite for many. Remember that improvements in insulin sensitivity are blunted by subclinical hypothyroidism and these patients will not respond to modifications in diet and exercise until their thyroid function improves.
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